Do not discount the fact that people are traveling to places within 50 miles of you. Anywhere there are hotels proves there is a demand for short-term stays.
From a purely financial perspective, you will want to choose a market with strong rental demand, low demand for property, and good prospects for property price and rental demand growth.
There is a rule of thumb that a good Airbnb should make 3x the long-term rental rate. You can find an estimate for the monthly rent on Zillow or Rentometer.